Loved Ones Search for Missing 53-Year-Old Woman in Southern California

Family and friends are searching for a missing Los Angeles County woman.

Jennifer Leann Issa, 53, was reported missing on Jan. 18, according to the Los Angeles County Sheriff’s Department.

Issa, considered at-risk, was last seen around 10 p.m. on the 23000 block of Mulholland Drive in Calabasas.

She is described as 5 feet 5 inches tall, weighing 150 pounds, with hazel eyes, brown hair, and a scar on her neck. At the time of her disappearance, she was wearing a black polo shirt and black pants.

Jennifer Leann Issa, 53, was last seen in Calabasas on Jan. 18, 2026. (Los Angeles County Sheriff’s Department)
She has a black and white English Cocker Spaniel service dog with her, along with a pink duffle bag.

It is unclear where she may have been heading. Her family noted that she has medical and mental health conditions and has not been heard from since, raising concerns for her safety.

Anyone with information on Issa’s whereabouts is urged to contact LASD’s Missing Persons Detail at 323-890-5500.

Anonymous tips can also be submitted to L.A. Regional Crime Stoppers at 1-800-222-8477 or online at lacrimestoppers.org

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